C5AR1 antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a(PubMed: 1847994, PubMed: 8182049, PubMed: 7622471, PubMed: 9553099, PubMed: 10636859, PubMed: 15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events(PubMed: 8182049, PubMed: 7622471, PubMed: 9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production(PubMed: 10636859, PubMed: 15153520). Immunogen: complement component 5a receptor 1 Synonyms: C5AR, C5R1 Observed MW: 45-50 kDa Uniprot ID: P21730 Reactivity: Human, Mouse, Rat Tested Application: ELISA, WB, IHC, IF, IP Recommended dilution: WB: 1: 500-1: 2000; IP: 1: 500-1: 1000; IHC: 1: 20-1: 200; IF: 1: 10-1: 100 Gene ID: 728 Research Area: Signal Transduction, Metabolism, Immunology