AMPK beta 2 antibody
Volume: 100 µg
Purification: Immunogen affinity purified
Form: liquid
Purity: 95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID:
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)
Background: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.
Immunogen: protein kinase, AMP-activated, beta 2 non-catalytic subunit
Synonyms: AMPK beta 2, AMPK subunit beta 2, PRKAB2
Observed MW: 35 kDa
Uniprot ID: O43741
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1: 500 - 1: 2000; IHC: 1: 50 - 1: 200
Gene ID: 5565
Research Area: Signal Transduction, Metabolism
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