AKR7A2 antibody
Volume: 100 µg
Purification: Immunogen affinity purified
Form: liquid
Purity: 95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID:
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)
Background: The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants.
Immunogen: aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
Synonyms: AFAR, AFAR1, AFB1 aldehyde reductase 1, AFB1 AR 1, AFB1 AR1, AKR7, AKR7A2, Aldoketoreductase 7, SSA reductase
Observed MW: 40 kDa
Uniprot ID: O43488
Reactivity: Human, Mouse
Tested Application: ELISA, WB, IHC, IF
Recommended dilution: WB: 1: 500 - 1: 2000; IHC: 1: 50 - 1: 200; IF: 1: 10 - 1: 100
Gene ID: 8574
Research Area: Metabolism
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