AHR antibody
Volume: 100 µg
Purification: Immunogen affinity purified
Form: liquid
Purity: 95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID:
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background: Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes(such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.
Immunogen: aryl hydrocarbon receptor
Synonyms: Ah receptor, AHR, aryl hydrocarbon receptor, bHLHe76
Observed MW: 105 kDa
Uniprot ID: P35869
Reactivity: Human, Mouse
Tested Application: ELISA, WB, IHC, IP
Recommended dilution: WB: 1: 200-1: 2000; IP: 1: 200-1: 2000; IHC: 1: 20-1: 200
Gene ID: 196
Research Area: Epigenetics, Signal Transduction, Metabolism
Internal Reference:
FNab00231