ADIPOQ antibody
Volume: 100 µg
Purification: Protein A+G purification
Form: liquid
Purity: 95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 6E1
Isotype: IgG2a
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background: Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
Immunogen: adiponectin, C1Q and collagen domain containing
Synonyms: ACDC, ACRP30, adiponectin, ADIPOQ, ADIPQTL1, ADPN, APM 1, APM1, GBP28, Gelatin binding protein
Observed MW: 26 kDa
Uniprot ID: Q15848
Reactivity: Human, Mouse
Tested Application: ELISA, WB
Recommended dilution: WB: 1: 500-1: 2000
Gene ID: 9370
Research Area: Signal Transduction, Metabolism
Internal Reference:
FNab00170