ACPP antibody
Volume: 100 µg
Purification: Protein A+G purification
Form: liquid
Purity: 95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 8D6
Isotype: IgG2a
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background: A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions(pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma. Isoform 2: the cellular form also has ecto-5'-nucleotidase activity in dorsal root ganglion(DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor. Acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling.
Immunogen: acid phosphatase, prostate
Synonyms: Acid phosphatase, prostate, ACP 3, ACP3, ACPP, PAP, Prostatic acid phosphatase
Observed MW: 48 kDa
Uniprot ID: P15309
Reactivity: Human, rat
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1: 200-1: 2000; IHC: 1: 20-1: 200
Gene ID: 55
Research Area: Cancer, Immunology, Metabolism