ABCB1 Antibody

Size : 50 µL Clone Number: 11H10 Aliases: Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD antigen CD243), ABCB1, MDR1 PGY1 Product Type: Recombinant Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P08183 Immunogen: A synthesized peptide derived from human ABCB1 Host: Reactivity: Human Tested Applications: ELISA, IHC, IF; Recommended dilution: IHC: 1: 50-1: 200, IF: 1: 50-1: 200 Background: Translocates drugs and phospholipids across the membrane (PubMed: 8898203, PubMed: 2897240, PubMed: 9038218). Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins (PubMed: 8898203). Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells (PubMed: 2897240, PubMed: 9038218). {ECO: 0000269|PubMed: 2897240, ECO: 0000269|PubMed: 8898203, ECO: 0000269|PubMed: 9038218}. Clonality: Monoclonal Isotype: Rabbit IgG Purification Method: Affinity-chromatography Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: ABCB1 Research Areas: Cancer; Metabolism; Signal transduction; Stem cells