CAPN2 Antibody

Size : 50 µL Clone Number: 17E9 Aliases: Calpain-2 catalytic subunit (EC 3.4.22.53) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (Calpain large polypeptide L2) (Calpain-2 large subunit) (Millimolar-calpain) (M-calpain), CAPN2, CANPL2 Product Type: Recombinant Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P17655 Immunogen: A synthesized peptide derived from human CAPN2 Host: Reactivity: Human Tested Applications: ELISA, WB; Recommended dilution: WB: 1: 500-1: 2000 Background: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed: 17650508). Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (By similarity). {ECO: 0000250|UniProtKB: O08529, ECO: 0000269|PubMed: 17650508}. Clonality: Monoclonal Isotype: Rabbit IgG Purification Method: Affinity-chromatography Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CAPN2 Research Areas: Cancer; Cell biology; Metabolism; Signal transduction