ANGPT2 Antibody
Size : 50 µL
Clone Number: 1F10
Aliases: Angiopoietin-2 (ANG-2), ANGPT2
Product Type: Recombinant Antibody
Immunogen Species: Homo sapiens (Human)
UniProt ID: O15123
Immunogen: A synthesized peptide derived from human Angiopoietin 2
Host:
Reactivity: Human
Tested Applications: ELISA, IHC; Recommended dilution: IHC: 1: 50-1: 200
Background: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
Clonality: Monoclonal
Isotype: Rabbit IgG
Purification Method: Affinity-chromatography
Conjugate: Non-conjugated
Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form: Liquid
Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names: ANGPT2
Research Areas: Cardiovascular
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