ANGPT2 Antibody

Size : 50 µL Clone Number: 1F10 Aliases: Angiopoietin-2 (ANG-2), ANGPT2 Product Type: Recombinant Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: O15123 Immunogen: A synthesized peptide derived from human Angiopoietin 2 Host: Reactivity: Human Tested Applications: ELISA, IHC; Recommended dilution: IHC: 1: 50-1: 200 Background: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. Clonality: Monoclonal Isotype: Rabbit IgG Purification Method: Affinity-chromatography Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: ANGPT2 Research Areas: Cardiovascular