Acetyl-Histone H2B type 1-B?K20?Antibody

Size : 50 µL Clone Number: 21F11 Aliases: Histone H2B type 1-B, Histone H2B.1, Histone H2B.f, H2B/f, HIST1H2BB, H2BFF Product Type: Recombinant Antibody Immunogen Species: Human UniProt ID: P33778 Immunogen: A synthesized peptide Host: Reactivity: Human, Mouse Tested Applications: ELISA, WB, ICC, IF, FC; Recommended dilution: WB: 1: 5000-1: 10000, ICC: 1: 50-1: 500, IF: 1: 30-1: 200 Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Clonality: Monoclonal Isotype: Rabbit IgG Purification Method: Affinity-chromatography Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: HIST1H2BB Research Areas: Epigenetics and Nuclear Signaling