ADAMTS18 Antibody

Size : 100 µL Clone Number: Aliases: ADAMTS18 antibody; ADAMTS21A disintegrin and metalloproteinase with thrombospondin motifs 18 antibody; ADAM-TS 18 antibody; ADAM-TS18 antibody; ADAMTS-18 antibody; EC 3.4.24.- antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q8TE60 Immunogen: Synthesized peptide derived from internal of Human ADAMTS18. Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB; WB: 1: 500-1: 3000 Background: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined. Cal S., Gene 283: 49-62(2002) [PubMed: 11867212]. Martin J., Nature 432: 988-994(2004) [PubMed: 15616553]. Ota T., Nat. Genet. 36: 40-45(2004) [PubMed: 14702039]. Clonality: Polyclonal Isotype: IgG Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: ADAMTS18 Research Areas: Cell biology;Signal transduction