ADRA1B Antibody

Size : 50 µL Clone Number: Aliases: ADA1B_HUMAN antibody; ADRA 1 antibody; Adra 1b antibody; ADRA1 antibody; ADRA1B antibody; Adrenergic alpha 1B receptor antibody; Adrenergic receptor alpha 1b antibody; Adrenoceptor alpha 1B antibody; Alpha 1 adrenergic receptor antibody; Alpha 1B adrenoceptor antibody; Alpha 1B adrenoreceptor antibody; Alpha-1B adrenergic receptor antibody; Alpha-1B adrenoceptor antibody; Alpha-1B adrenoreceptor antibody; Alpha1 adrenergic receptor antibody; Alpha1B adrenergic receptor antibody; Alpha1BAR antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P35368 Immunogen: Synthetic peptide of Human ADRA1B Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB, IHC; ELISA: 1: 1000-1: 5000, WB: 1: 200-1: 1000, IHC: 1: 25-1: 100 Background: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: ADRA1B Research Areas: Neuroscience