ABCG5 Antibody

Size : 50 µL Clone Number: Aliases: Abcg5 antibody; ABCG5_HUMAN antibody; ATP binding cassette sub family G (WHITE) member 5 (sterolin 1) antibody; ATP binding cassette sub family G member 5 antibody; ATP-binding cassette sub-family G member 5 antibody; ATP-binding cassette; sub-family G (WHITE); member 5 antibody; Sterolin 1 antibody; Sterolin-1 antibody; STSL antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9H222 Immunogen: Synthetic peptide of Human ABCG5 Host: Rabbit Reactivity: Human Tested Applications: ELISA, IHC; ELISA: 1: 2000-1: 5000, IHC: 1: 25-1: 100 Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: ABCG5 Research Areas: Cancer Cardiovascular;Metabolism;Signal transduction