CARD11 Antibody

Size : 100 µL Clone Number: Aliases: 0610008L17Rik antibody; 2410011D02Rik antibody; Bcl10 interacting maguk protein 3 antibody; BIMP 3 antibody; BIMP3 antibody; CAR11_HUMAN antibody; CARD 11 antibody; CARD containing MAGUK protein 3 antibody; Card maguk protein 1 antibody; CARD-containing MAGUK protein 1 antibody; CARD11 antibody; CARD11 protein antibody; Carma 1 antibody; CARMA1 antibody; Caspase recruitment domain containing protein 11 antibody; Caspase recruitment domain family member 11 antibody; Caspase recruitment domain-containing protein 11 antibody; MGC133069 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9BXL7 Immunogen: Synthesized peptide derived from internal of Human CARD11. Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB; WB: 1: 500-1: 3000 Background: Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10. Bertin J., J. Biol. Chem. 276: 11877-11882(2001). Gaide O., FEBS Lett. 496: 121-127(2001). Hillier L.W., Nature 424: 157-164(2003). Clonality: Polyclonal Isotype: IgG Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CARD11 Research Areas: Epigenetics and Nuclear Signaling;Cancer;Cell biology;Immunology;Signal transduction