ADRBK1 Antibody

Size : 100 µL Clone Number: Aliases: ADRBK1 antibody; Adrenergic beta receptor kinase 1 antibody; ARBK1_HUMAN antibody; BARK antibody; BARK1 antibody; Beta adrenergic receptor kinase 1 antibody; Beta ARK 1 antibody; Beta ARK1 antibody; Beta-adrenergic receptor kinase 1 antibody; Beta-ARK-1 antibody; FLJ16718 antibody; G protein coupled receptor kinase 2 antibody; G-protein coupled receptor kinase 2 antibody; GRK2 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P25098 Immunogen: Synthesized peptide derived from internal of Human ARBK1. Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB; WB: 1: 500-1: 3000 Background: Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner. Chuang T.T., J. Biol. Chem. 267: 6886-6892(1992). Penn R.B., J. Biol. Chem. 269: 14924-14930(1994). Fushman D., J. Biol. Chem. 273: 2835-2843(1998). Clonality: Polyclonal Isotype: IgG Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: GRK2 Research Areas: Neuroscience;Signal transduction