AFF4 Antibody, HRP conjugated

Size : 50 µg Clone Number: Aliases: AFF4 antibody; AF5Q31 antibody; MCEF antibody; HSPC092 antibody; AF4/FMR2 family member 4 antibody; ALL1-fused gene from chromosome 5q31 protein antibody; Protein AF-5q31 antibody; Major CDK9 elongation factor-associated protein antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9UHB7 Immunogen: Recombinant Human AF4/FMR2 family member 4 protein (77-334AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA Background: Key component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by Key component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. In the SEC complex, AFF4 acts as a central scaffold that recruits other factors through direct interactions with ELL proteins (ELL, ELL2 or ELL3) and the P-TEFb complex. In case of infection by HIV-1 virus, the SEC complex is recruited by the viral Tat protein to stimulate viral gene expression. Clonality: Polyclonal Isotype: IgG Purification Method: 95%, Protein G purified Conjugate: HRP Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: AFF4 Research Areas: Epigenetics and Nuclear Signaling; Cell biology