AADACL2 Antibody

Size : 50 µL Clone Number: Aliases: AADACL2Arylacetamide deacetylase-like 2 antibody; EC 3.1.1.- antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q6P093 Immunogen: Fusion protein of Human AADACL2 Host: Rabbit Reactivity: Human Tested Applications: ELISA, IHC; ELISA: 1: 2000-1: 5000, IHC: 1: 25-1: 100 Background: AADAC is a 45 kDa membrane-associated hydrolase highly expressed in the human liver that has been implicated in the hydrolysis of arylacetamide xenobiotics including flutamide and phenacetin.556–560AADAC is highly homologous to several related lipases, AADACL1, 2, and 4, the latter two of which remain completely unannotated. Overexpression of AADAC in a rat hepatoma cell line produces changes in cellular TG levels, apoplipoprotein B secretion, and fatty acid oxidation, but the mechanism for these effects remains unclear.561 Candidate endogenous substrates, selective inhibitors, or knockout mice have not, to our knowledge, been described for AADAC or the related enzymes AADACL2 and AADACL4. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: AADACL2 Research Areas: Cancer;Metabolism;Signal transduction