ALS2 Antibody
Size : 50 µL
Clone Number:
Aliases: ALS 2 antibody; ALS2 antibody; ALS2_HUMAN antibody; ALS2CR6 antibody; Alsin antibody; ALSJ antibody; Amyotrophic lateral sclerosis 2 (juvenile) antibody; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 6 antibody; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein antibody; Amyotrophic lateral sclerosis 2 protein antibody; Amyotrophic lateral sclerosis protein 2 antibody; FLJ31851 antibody; IAHSP antibody; KIAA1563 antibody; MGC87187 antibody; PLSJ antibody
Product Type: Polyclonal Antibody
Immunogen Species: Homo sapiens (Human)
UniProt ID: Q96Q42
Immunogen: Fusion protein of Human ALS2
Host: Rabbit
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IHC; ELISA: 1: 2000-1: 5000, IHC: 1: 25-1: 100
Background: The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality: Polyclonal
Isotype: IgG
Purification Method: Antigen affinity purification
Conjugate: Non-conjugated
Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form: Liquid
Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names: ALS2
Research Areas: Neuroscience
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