ACTN2 Antibody

Size : 50 µL Clone Number: Aliases: Actin binding protein antibody; Actinin alpha 2 antibody; ACTN 2 antibody; ACTN2 antibody; ACTN2_HUMAN antibody; Alpha actinin 2 antibody; Alpha actinin skeletal muscle antibody; Alpha actinin skeletal muscle isoform 2 antibody; Alpha-actinin skeletal muscle isoform 2 antibody; Alpha-actinin-2 antibody; CMD1AA antibody; F actin cross linking protein antibody; F-actin cross-linking protein antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P35609 Immunogen: Synthetic peptide of Human ACTN2 Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB, IHC; ELISA: 1: 2000-1: 5000, WB: 1: 500-1: 2000, IHC: 1: 25-1: 100 Background: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: ACTN2 Research Areas: Cardiovascular;Signal transduction