AFF1 Antibody

Size : 100 µL Clone Number: Aliases: AF 4 antibody; AF 4 protein antibody; AF4 antibody; AF4-MLL antibody; AF4/FMR2 family member 1 antibody; AFF 1 antibody; AFF1 antibody; AFF1_HUMAN antibody; ALL1 fused gene from chromosome 4 antibody; ALL1-fused gene from chromosome 4 protein antibody; FEL antibody; MGC134969 antibody; MLL/AF4 antibody; MLLT2 antibody; myeloid/lymphoid or mixed lineage leukemia (trithorax homolog; Drosophila); translocated to; 2 antibody; MYELOID/LYMPHOID OR MIXED LINEAGE LEUKEMIA TRANSLOCATED TO 2; MLLT2 antibody; PBM1 antibody; Pre B cell monocytic leukemia partner 1 antibody; Protein AF-4 antibody; Protein FEL antibody; Proto-oncogene AF4 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P51825 Immunogen: Synthesized peptide derived from N-terminal of Human AF4. Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, IHC; IHC: 1: 50-1: 100 Background: A chromosomal aberration involving AFF1 is associated with acute leukemias. Translocation t(4;11)(q21;q23) with MLL/HRX. The result is a rogue activator protein. Belongs to the AF4 family.?Nakamura T., Proc. Natl. Acad. Sci. U.S.A. 90: 4631-4635(1993).Morrissey J., Blood 81: 1124-1131(1993).Gu Y., Cell 71: 701-708(1992). Clonality: Polyclonal Isotype: IgG Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: AFF1 Research Areas: Epigenetics and Nuclear Signaling;Cancer