ACVRL1 Antibody
Size : 100 µL
Clone Number:
Aliases: Activin A receptor antibody; Activin A receptor type II like 1 antibody; Activin A receptor; type II like kinase 1 antibody; Activin receptor like kinase 1 antibody; Activin receptor-like kinase 1 antibody; ACVL1_HUMAN antibody; ACVRL1 antibody; ACVRLK1 antibody; ALK-1 antibody; ALK1 antibody; HHT antibody; HHT2 antibody; ORW2 antibody; Osler Rendu Weber syndrome 2 antibody; Serine/threonine protein kinase receptor R3 antibody; Serine/threonine-protein kinase receptor R3 antibody; SKR3 antibody; TGF B superfamily receptor type I antibody; TGF-B superfamily receptor type I antibody; TSR-I antibody; TSR1 antibody
Product Type: Polyclonal Antibody
Immunogen Species: Homo sapiens (Human)
UniProt ID: P37023
Immunogen: Synthesized peptide derived from internal of Human ACVL1.
Host: Rabbit
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB, IHC, IF; WB: 1: 500-1: 3000, IHC: 1: 50-1: 100, IF: 1: 100-1: 500
Background: Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
ten Dijke P., Oncogene 8: 2879-2887(1993).
Attisano L., Cell 75: 671-680(1993).
Berg J.N., Am. J. Hum. Genet. 61: 60-67(1997).
Clonality: Polyclonal
Isotype: IgG
Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conjugate: Non-conjugated
Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form: liquid
Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names: ACVRL1
Research Areas: Cancer Cardiovascular;Metabolism;Signal transduction