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AMACR Antibody

https://www.academycancerimmunology.org/web/image/product.template/4080/image_1920?unique=d05de28
Size : 50 µL Clone Number: Aliases: 2 arylpropionyl CoA epimerase antibody; 2 methylacyl CoA racemase antibody; 2-methylacyl-CoA racemase antibody; Alpha methylacyl CoA racemase antibody; Alpha methylacyl Coenzyme A racemase antibody; Alpha methylacyl-CoA racemase deficiency; included antibody; Alpha-methylacyl-CoA racemase antibody; Amacr antibody; AMACR deficiency; included antibody; AMACR_HUMAN antibody; CBAS4 antibody; Da1-8 antibody; EC 5.1.99.4 antibody; Macr1 antibody; Methylacyl CoA racemase alpha antibody; RACE antibody; RM antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9UHK6 Immunogen: Fusion protein of Human AMACR Host: Rabbit Reactivity: Human Tested Applications: ELISA, WB, IHC; ELISA: 1: 2000-1: 5000, WB: 1: 500-1: 2000, IHC: 1: 25-1: 100 Background: This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: AMACR Research Areas: Cell biology;Metabolism;Signal transduction

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