AC1 Antibody, Biotin conjugated

Size : 50 µg Clone Number: Aliases: AC1 antibody; AL1 antibody; Replication-associated protein antibody; Rep antibody; EC 2.7.7.- antibody; EC 3.1.21.- antibody; 40.4 kDa protein antibody; Protein AC1 antibody; Protein AL1 antibody Product Type: Polyclonal Antibody Immunogen Species: African cassava mosaic virus (isolate West Kenyan 844) (ACMV) (Cassava latent virus (isolate West Kenyan 844)) UniProt ID: P14982 Immunogen: Recombinant African cassava mosaic virus Replication-associated protein (1-358AA) Host: Rabbit Reactivity: African cassava mosaic virus Tested Applications: ELISA Background: Essential for the replication of viral ssDNA. The closed circular ssDNA genome is first converted to a superhelical dsDNA. Rep binds a specific region at the genome origin of replication. It introduces an endonucleolytic nick within the conserved sequence 5\'-TAATATTAC-3\' in the intergenic region of the genome present in all geminiviruses, thereby initiating the rolling circle replication (RCR). Following cleavage, binds covalently to the 5\'-phosphate of DNA as a tyrosyl ester. The cleavage gives rise to a free 3\'-OH that serves as a primer for the cellular DNA polymerase. The polymerase synthesizes the (+) strand DNA by rolling circle mechanism. After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication. Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities (By similarity). Clonality: Polyclonal Isotype: IgG Purification Method: 95%, Protein G purified Conjugate: Biotin Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: AC1 Research Areas: Others