ALDH1A1/ALDH1A2/ALDH1A3 Antibody

Size : 50 µL Clone Number: Aliases: Aldehyde dehydrogenase 1 family, member A1/2/3 Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P00352/O94788/P47895 Immunogen: Fusion protein of Human ALDH1A1/ALDH1A2/ALDH1A3 Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB, IHC; ELISA: 1: 1000-1: 5000, WB: 1: 500-1: 2000, IHC: 1: 50-1: 150 Background: This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: ALDH1A1/ALDH1A2/ALDH1A3 Research Areas: Neuroscience?Cancer;Stem cells