ACVR1 Antibody

Size : 50 µL Clone Number: Aliases: Activin A receptor type I antibody; Activin A receptor type II like kinase 2 antibody; Activin receptor type I antibody; Activin receptor type-1 antibody; Activin receptor-like kinase 2 antibody; ACTR-I antibody; ACTRI antibody; Acvr1 antibody; ACVR1_HUMAN antibody; ACVR1A antibody; ACVRLK2 antibody; ALK 2 antibody; ALK-2 antibody; ALK2 antibody; FOP antibody; Hydroxyalkyl protein kinase antibody; Serine/threonine-protein kinase receptor R1 antibody; SKR1 antibody; TGF-B superfamily receptor type I antibody; TGFB superfamily receptor type I antibody; TSR-I antibody; TSRI antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q04771 Immunogen: Fusion protein of Human ACVR1 Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, IHC; ELISA: 1: 1000-1: 5000, IHC: 1: 50-1: 200 Background: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: ACVR1 Research Areas: Epigenetics and Nuclear Signaling;Signal transduction?Stem cells