AGBL2 Antibody

Size : 50 µL Clone Number: Aliases: AGBL 2 antibody; AGBL2 antibody; ATP/GTP binding protein like 2 antibody; ATP/GTP-binding protein-like 2 antibody; Carboxypeptidase 2 cytosolic antibody; CBPC2_HUMAN antibody; CCP2 antibody; Cytosolic carboxypeptidase 2 antibody; FLJ23598 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q5U5Z8 Immunogen: Fusion protein of Human AGBL2 Host: Rabbit Reactivity: Human Tested Applications: ELISA, IHC; ELISA: 1: 2000-1: 5000, IHC: 1: 25-1: 100 Background: Metallocarboxypeptidase that may play a role in the processing of tubulin. Knockdown of AGBL2 results in a failure of the cell to detyrosinate the C-terminal EEY region of ?-tubulin and indicates that, it is a candidate for the long sought after tubulin tyrosine carboxypeptidase important in regulation of microtubule dynamics. RARRES1, its interacting partners AGBL2, Eg5/KIF11, another EEY bearing protein (EB1), and the microtubule tyrosination cycle are important in tumorigenesis and identify a novel area for therapeutic intervention. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: AGBL2 Research Areas: Signal transduction