AGXT Antibody
Size : 50 µL
Clone Number:
Aliases: AGT antibody; AGT1 antibody; Agxt antibody; AGXT1 antibody; Alanine glyoxylate aminotransferase antibody; Alanine glyoxylate aminotransferase3 antibody; Alanine--glyoxylate aminotransferase antibody; EC 2.6.1.44 antibody; EC 2.6.1.51 antibody; Hepatic peroxisomal alanine glyoxylate aminotransferase antibody; Hepatic peroxisomal alanine: glyoxylate aminotransferase antibody; L alanine glyoxylate aminotransferase 1 antibody; MS773 antibody; PH1 antibody; Serine pyruvate aminotransferase antibody; Serine--pyruvate aminotransferase antibody; Serine--pyruvate aminotransferase, mitochondrial antibody; Serine: pyruvate aminotransferase antibody; SPAT antibody; SPT antibody; SPYA_HUMAN antibody; TLH6 antibody
Product Type: Polyclonal Antibody
Immunogen Species: Homo sapiens (Human)
UniProt ID: P21549
Immunogen: Synthetic peptide of Human AGXT
Host: Rabbit
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB; ELISA: 1: 1000-1: 2000, WB: 1: 200-1: 1000
Background: Serine—pyruvate aminotransferase is an enzyme that in humans is encoded by the AGXT gene. This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. Defects in AGXT are the cause of hyperoxaluria primary type 1 (HP1), also known as primary hyperoxaluria type I (PH1) and oxalosis I. HP1 is a rare autosomal recessive inborn error of glyoxylate metabolism characterized by increased excretion of oxalate and glycolate, and the progressive accumulation of insoluble calcium oxalate in the kidney and urinary tract.
Clonality: Polyclonal
Isotype: IgG
Purification Method: Antigen affinity purification
Conjugate: Non-conjugated
Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form: Liquid
Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names: AGXT
Research Areas: Metabolism;Signal transduction
Internal Reference:
CSB-PA198331