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ANGPTL3 Antibody

https://www.academycancerimmunology.org/web/image/product.template/4426/image_1920?unique=d05de28
Size : 100 µL Clone Number: Aliases: Angiopoietin-related protein 3, FHBL2, ANGPT5 Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9Y5C1 Immunogen: Fusion protein corresponding to C terminal 300 amino acids of Human Angiopoietin-related protein 3 Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB, IHC; WB: 1: 500-1: 1000, IHC: 1: 50-1: 200 Background: The protein encoded by this gene is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis. Clonality: Polyclonal Isotype: IgG Purification Method: Affinity purification Conjugate: Non-conjugated Buffer: Supplied at 0.8mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: ANGPTL3 Research Areas: Others

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