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ACVR2A Antibody

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Size : 50 µL Clone Number: Aliases: Activin A receptor type IIA antibody; Activin receptor type 2A antibody; Activin receptor type IIA antibody; Activin receptor type-2A antibody; ACTR 2 antibody; ACTR IIA antibody; ACTR-IIA antibody; ACTR2 antibody; ACTRII antibody; ACTRIIA antibody; Acvr 2 antibody; Acvr 2A antibody; Acvr2 antibody; ACVR2A antibody; AVR2A_HUMAN antibody; OTTHUMP00000197918 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P27037 Immunogen: Fusion protein of Human ACVR2A Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB; ELISA: 1: 2000-1: 5000, WB: 1: 500-1: 2000 Background: This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: ACVR2A Research Areas: Cancer;Metabolism;Signal transduction?Stem cells

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Internal Reference: CSB-PA110386