ANAPC1 Antibody

Size : 100 µL Clone Number: Aliases: ANAPC 1 antibody; Anapc1 antibody; Anaphase promoting complex subunit 1 antibody; anaphase-promoting complex 1 (meiotic checkpoint regulator) antibody; Anaphase-promoting complex subunit 1 antibody; Apc 1 antibody; APC1 antibody; APC1_HUMAN antibody; Cyclosome subunit 1 antibody; MCPR antibody; Meiotic checkpoint regulator antibody; Mitotic checkpoint regulator antibody; Protein Tsg 24 antibody; Protein Tsg24 antibody; Testis-specific gene 24 protein antibody; TSG 24 antibody; TSG24 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9H1A4 Immunogen: Synthesized peptide derived from Internal of Human APC1. Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, IHC; IHC: 1: 50-1: 100 Background: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Joergensen P.M., Gene 262: 51-59(2001). Ota T., Nat. Genet. 36: 40-45(2004). Kraft C., EMBO J. 22: 6598-6609(2003). Clonality: Polyclonal Isotype: IgG Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: ANAPC1 Research Areas: Cell biology