ADSL Antibody
Size : 50 µL
Clone Number:
Aliases: Adenylosuccinase antibody; Adenylosuccinate lyase antibody; ADSL antibody; AMPS antibody; ASase antibody; ASL antibody; OTTHUMP00000199172 antibody; OTTHUMP00000199173 antibody; PUR8_HUMAN antibody
Product Type: Polyclonal Antibody
Immunogen Species: Homo sapiens (Human)
UniProt ID: P30566
Immunogen: Fusion protein of Human ADSL
Host: Rabbit
Reactivity: Human, Mouse
Tested Applications: ELISA, IHC; ELISA: 1: 1000-1: 2000, IHC: 1: 15-1: 50
Background: Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene.
Clonality: Polyclonal
Isotype: IgG
Purification Method: Antigen affinity purification
Conjugate: Non-conjugated
Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form: Liquid
Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names: ADSL
Research Areas: Metabolism;Signal transduction
Internal Reference:
CSB-PA073477