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ADSL Antibody

https://www.academycancerimmunology.org/web/image/product.template/2580/image_1920?unique=b611535
Size : 50 µL Clone Number: Aliases: Adenylosuccinase antibody; Adenylosuccinate lyase antibody; ADSL antibody; AMPS antibody; ASase antibody; ASL antibody; OTTHUMP00000199172 antibody; OTTHUMP00000199173 antibody; PUR8_HUMAN antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P30566 Immunogen: Fusion protein of Human ADSL Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, IHC; ELISA: 1: 1000-1: 2000, IHC: 1: 15-1: 50 Background: Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: ADSL Research Areas: Metabolism;Signal transduction

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Internal Reference: CSB-PA073477