AGRP Antibody, Biotin conjugated

Size : 50 µg Clone Number: Aliases: Agouti related neuropeptide antibody; Agouti Related Protein Homolog antibody; Agouti-related protein antibody; Agrp antibody; AGRP_HUMAN antibody; AGRT antibody; ART antibody; ASIP2 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: O00253 Immunogen: Recombinant Human Agouti-related protein (83-132AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA Background: Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R (By similarity). Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner. Clonality: Polyclonal Isotype: IgG Purification Method: 95%, Protein G purified Conjugate: Biotin Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: AGRP Research Areas: Neuroscience; Cardiovascular; Metabolism; Signal transduction