AFG3L2 Antibody, FITC conjugated
Size : 50 µg
Clone Number:
Aliases: AFG3 (ATPase family gene 3; yeast) like 2 antibody; AFG3 ATPase family gene 3 like 2 (yeast) antibody; AFG3 ATPase family gene 3 like 2 antibody; AFG3 like protein 2 antibody; AFG3-like protein 2 antibody; AFG32_HUMAN antibody; AFG3L2 antibody; ATPase family gene 3 like 2 antibody; ATPase family gene 3 yeast antibody; EC 3.4.24.- antibody; FLJ25993 antibody; Paraplegin like protein antibody; Paraplegin-like protein antibody; SCA28 antibody; Spinocerebellar ataxia 28 antibody
Product Type: Polyclonal Antibody
Immunogen Species: Homo sapiens (Human)
UniProt ID: Q9Y4W6
Immunogen: Recombinant Human AFG3-like protein 2 protein (550-759AA)
Host: Rabbit
Reactivity: Human
Tested Applications:
Background: ATP-dependent protease which is essential for axonal and neuron development. In neurons, mediates degradation of SMDT1/EMRE before its assembly with the uniporter complex, limiting the availability of SMDT1/EMRE for MCU assembly and promoting efficient assembly of gatekeeper subunits with MCU (PubMed: 27642048). Required for the maturation of paraplegin (SPG7) after its cleavage by mitochondrial-processing peptidase (MPP), converting it into a proteolytically active mature form (By similarity).
Clonality: Polyclonal
Isotype: IgG
Purification Method: 95%, Protein G purified
Conjugate: FITC
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form: Liquid
Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names: AFG3L2
Research Areas: Neuroscience; Cancer; Cell biology; Metabolism; Signal transduction
Internal Reference:
CSB-PA04005C0Rb