ADAM15 Antibody
Size : 50 µg
Clone Number:
Aliases: A disintegrin and metalloproteinase domain 15 (metargidin) antibody; A disintegrin and metalloproteinase domain 15 antibody; ADA15_HUMAN antibody; ADAM 15 antibody; ADAM metallopeptidase domain 15 antibody; Adam15 antibody; and cysteine-rich protein 15 antibody; Disintegrin and metalloproteinase domain-containing protein 15 antibody; disintegrin-like antibody; EC 3.4.24. antibody; MDC 15 antibody; MDC-15 antibody; MDC15 antibody; Metalloprotease RGD disintegrin protein antibody; Metalloproteinase like disintegrin like and cysteine rich protein 15 antibody; Metalloproteinase-like antibody; Metargidin antibody
Product Type: Polyclonal Antibody
Immunogen Species: Homo sapiens (Human)
UniProt ID: Q13444
Immunogen: Recombinant Human Disintegrin and metalloproteinase domain-containing protein 15 protein (207-452AA)
Host: Rabbit
Reactivity: Human
Tested Applications: ELISA, IHC; Recommended dilution: IHC: 1: 20-1: 200
Background: Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation. Cleaves E-cadherin in response to growth factor deprivation. Plays a role in glomerular cell migration. Plays a role in pathological neovascularization. May play a role in cartilage remodeling. May be proteolytically processed, during sperm epididymal maturation and the acrosome reaction. May play a role in sperm-egg binding through its disintegrin domain.
Clonality: Polyclonal
Isotype: IgG
Purification Method: 95%, Protein G purified
Conjugate: Non-conjugated
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form: Liquid
Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names: ADAM15
Research Areas: Cancer; Cell biology; Signal transduction
Internal Reference:
CSB-PA01915A0Rb