ALOX12B Antibody, Biotin conjugated
Size : 50 µL
Clone Number:
Aliases: ALOX12B antibody; Arachidonate 12-lipoxygenase antibody; 12R-type antibody; 12R-LOX antibody; 12R-lipoxygenase antibody; EC 1.13.11.- antibody; Epidermis-type lipoxygenase 12 antibody
Product Type: Polyclonal Antibody
Immunogen Species: Homo sapiens (Human)
UniProt ID: O75342
Immunogen: Recombinant Human Arachidonate 12-lipoxygenase, 12R-type protein (484-663AA)
Host: Rabbit
Reactivity: Human
Tested Applications: ELISA
Background: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to (12R)-hydroperoxyeicosatetraenoic acid/(12R)-HPETE and minor stereoisomers. In the skin, acts upstream of ALOXE3 on the lineolate moiety of esterified omega-hydroxyacyl-sphingosine (EOS) ceramides to produce an epoxy-ketone derivative, a crucial step in the conjugation of omega-hydroxyceramide to membrane proteins. Therefore plays a crucial role in the synthesis of corneocytes lipid envelope and the establishment of the skin barrier to water loss. May also play a role in the regulation of the expression of airway mucins.
Clonality: Polyclonal
Isotype: IgG
Purification Method: 95%, Protein G purified
Conjugate: Biotin
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form: Liquid
Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names: ALOX12B
Research Areas: Cardiovascular; Cell biology; Metabolism; Signal transduction
Our Products !
Check out what's in our lab !
Your Dynamic Snippet will be displayed here... This message is displayed because you did not provide both a filter and a template to use.