AKR1C4 Antibody

Size : 50 µL Clone Number: Aliases: 3 alpha HSD1 antibody; 3-alpha-HSD1 antibody; 3-alpha-hydroxysteroid dehydrogenase type I antibody; AK1C4_HUMAN antibody; AKR1C4 antibody; Aldo keto reductase family 1 member C4 antibody; Aldo-keto reductase family 1 member C4 antibody; CDR antibody; Chlordecone reductase antibody; DD-4 antibody; DD4 antibody; Dihydrodiol dehydrogenase 4 antibody; HAKRA antibody; HSD3a antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P17516 Immunogen: Recombinant Human Aldo-keto reductase family 1 member C4 protein (1-323AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA, IHC; Recommended dilution: IHC: 1: 20-1: 200 Background: Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen Affinity Purified Conjugate: Non-conjugated Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: AKR1C4 Research Areas: Cancer; Metabolism; Signal transduction