AKAP10 Antibody
Size : 50 µL
Clone Number:
Aliases: AKAP10A-kinase anchor protein 10 antibody; mitochondrial antibody; AKAP-10 antibody; Dual specificity A kinase-anchoring protein 2 antibody; D-AKAP-2 antibody; Protein kinase A-anchoring protein 10 antibody; PRKA10 antibody
Product Type: Polyclonal Antibody
Immunogen Species: Homo sapiens (Human)
UniProt ID: O43572
Immunogen: Recombinant Human A-kinase anchor protein 10, mitochondrial protein (413-662AA)
Host: Rabbit
Reactivity: Human
Tested Applications: ELISA, WB, IHC; Recommended dilution: WB: 1: 200-1: 1000, IHC: 1: 20-1: 200
Background: Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase (By similarity).
Clonality: Polyclonal
Isotype: IgG
Purification Method: Antigen Affinity Purified
Conjugate: Non-conjugated
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form: Liquid
Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names: AKAP10
Research Areas: Signal transduction
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