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AICDA Antibody

https://www.academycancerimmunology.org/web/image/product.template/3030/image_1920?unique=b611535
Size : 50 µg Clone Number: Aliases: Activation induced cytidine deaminase antibody; Activation induced deaminase antibody; Activation-induced cytidine deaminase antibody; AICDA antibody; AICDA_HUMAN antibody; AID antibody; ARP 2 antibody; ARP2 antibody; CDA 2 antibody; CDA2 antibody; Cytidine aminohydrolase antibody; HIGM2 antibody; Integrated into Burkitt's lymphoma cell line Ramos antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9GZX7 Immunogen: Recombinant Human Single-stranded DNA cytosine deaminase protein (1-60AA) Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB; Recommended dilution: WB: 1: 1000-1: 5000 Background: Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class-switch recombination in B-lymphocytes. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. Clonality: Polyclonal Isotype: IgG Purification Method: 95%, Protein G purified Conjugate: Non-conjugated Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: AICDA Research Areas: Epigenetics and Nuclear Signaling; Immunology

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