CD19 Monoclonal Antibody,Biotin Conjugated

Size : 100 µL Clone Number: Aliases: Product Type: Monoclonal Antibody Immunogen Species: Human UniProt ID: P15391 Immunogen: Recombinant Protein Host: Mouse Reactivity: Human Tested Applications: ELISA,IF,FC;Recommended dilution: IF: 1: 100-1: 200 Background: COC19 reacts with CD19 (B4), a 90 kDa molecule, which is expressed on approximately 5-25% of human peripheral blood lymphocytes. CD19 antigen is present on human B lymphocytes at most stages of maturation, from the earliest Ig gene rearrangement in pro-B cells to mature cell, as well as malignant B cells, but is lost on maturation to plasma cells. CD19 antibody does not react with T lymphocytes, monocytes and granulocytes. CD19 is a critical signal transduction molecule that regulates B lymphocyte development, activation and differentiation. This clone is cross reactive with non-human primate.* CD19 is a key phenotyping marker of non-T cell leukemia.1. Nadler, LM et al. (1983) J. Immunol. 131: 2442. Schlossman, SL et al., eds. (1995) Leucocyte Typing V: White Cell Differentiation Antigens, Oxford University Press, New York.3. Tedder T. et al. (1994) Immunol Today. 15: 437-442 Clonality: Monoclonal Isotype: IgG1 Purification Method: Affinity purified Conjugate: Non-conjugated Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CD19 Research Areas: Immunology;Stem cells