CD14 Monoclonal Antibody,Purified

Size : 100 µL Clone Number: Aliases: Product Type: Monoclonal Antibody Immunogen Species: Human UniProt ID: P08571 Immunogen: Recombinant Protein Host: Mouse Reactivity: Human Tested Applications: ELISA,IF,FC;Recommended dilution: IF: 1: 100-1: 200 Background: 4AW4 reacts with CD14, a 53-55 kDa molecule. CD14 is a human high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS-endotoxin) and serum LPS-binding protein (LPB). CD14 antigen has a strong presence on the surface of monocytes/macrophages, is weakly expressed on granulocytes, but not expressed by myeloid progenitor cells. CD14 functions as a receptor for endotoxin; when the monocytes become activated they release cytokines such as TNF, and up-regulate cell surface molecules including adhesion molecules.This clone is cross reactive with non-human primate.1. Knapp, W et al., eds. (1989) Leucocyte Typing IV : White Cell Differentiation Antigens, Oxford University Press, New York.2. Makgoba, MW et al., (1988) Nature 331: 86-883. Boyd. AW et al. (1989) Blood 73: 1896-1903 Clonality: Monoclonal Isotype: IgG1 Purification Method: Affinity purified Conjugate: Non-conjugated Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CD14 Research Areas: Immunology;Stem cells